Job number: ACAD103724
Division/School: Bristol Medical School
Contract type: Open Ended
Working pattern: Full time
Salary: £37,345 - £42,036 per annum (Grade J) / £43,267 - £48,677 per annum (Grade K)
Closing date for applications: 3rd February 2019
We are recruiting a researcher with a background in statistics, genetic epidemiology, or statistical genetics to join Professor George Davey Smith’s research group based within the MRC Integrative Epidemiology Unit at the University of Bristol (MRC IEU).
You will focus on identification of causal risk factors for disease progression. Most studies of disease aetiology investigate disease onset as the outcome of interest (e.g. comparing diseased cases with controls).
We hypothesise that there may be alternative mechanisms that influence the progression of disease after onset.
Identification of these will be valuable in informing the treatment of disease and may explain why some interventions (based on onset aetiological evidence) fail.
To date, few studies have addressed the aetiology of disease progression, in part due to the relative shortage of necessary data and the need for development of statistical methods that account for the potential bias induced in case-only studies.
Within the MRC IEU we have access to large datasets of disease progression phenotypes and have a programme of methodological development in this area, to allow this type of research to be possible.
The successful candidate will have a strong statistical or genetics background, with experience using Stata, R and other programming languages and experience working with a range of large-scale data sources.
You will also have experience of applied statistical analysis and will have a good understanding of genome-wide association and Mendelian randomization methods.
The successful candidate will be appointed at either Senior Research Associate (grade J) or Research Fellow (grade K) depending on experience.
Interested applicants are strongly encouraged to contact Professor George Davey Smith (email@example.com) and Dr Lavinia Paternoster (firstname.lastname@example.org).
We appreciate and value difference, seeking to attract, develop and retain a diverse mix of talented people that will contribute to the overall success of Bristol and help maintain our position as one of the world’s leading universities.